Rami Malek is Charlie Heller, a brilliant, but deeply introverted CIA decoder working out of a basement office at headquarters in Langley. His life is turned upside down when his wife is killed in a London terrorist attack. With his supervisors refusing to take action, he takes matters into his own hands and embarks on a dangerous trek across the globe to track down those responsible, with his intelligence serving as the ultimate weapon for eluding his pursuers and achieving his revenge.